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"One type of depressive illness is bipolar disorder (or manic depressive illness) which is characterized by cycling mood changes: severe highs (mania) and lows (depression), often with periods of normal mood in between."
"The Food and Drug Administration issued a Public Health Advisory on February 10, 2000 that stated that St Johns wort appears to affect an important metabolic pathway that is used by many drugs prescribed to treat conditions such as AIDS, heart disease, depression, seizures, certain cancers, and rejection of transplants and therefore, health care providers should alert their patients about these potential drug interactions."
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