"Although available therapies alleviate symptoms in over 80 percent of those treated, less than half of people with depression get the help they need."

"Antianxiety drugs or sedatives are not antidepressants but they are sometimes prescribed along with antidepressants; however, they are not effective when taken alone for a depressive disorder."

 

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"While studies generally indicate that about 25 percent of people with cancer have depression, only 2 percent of cancer patients in one study were receiving antidepressant medication."

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  • An NIMH funded clinical trial of 439 adolescents with major depression found that a combination of medication and psychotherapy is the most effective treatment.
  • The risk of developing bipolar disorder remains approximately equal for males and females throughout adolescence and adulthood.
  • Medications alone appear to be helpful in approximately 50% of the cases.
  • Before puberty, boys and girls are equally likely to develop depressive disorders, but after age 14, females are twice as likely as males to have major depression or dysthymia.
  • In the United States, researchers estimate that in any given one year period, depressive illnesses affect 12 percent of women (more than 12 million women) and nearly 7 percent of men (more than six million men).

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"For individuals with bipolar disorder and those with chronic or recurrent major depression, medication may have to be maintained indefinitely."

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"More than half of people with bipolar disorder type I (with severe mania) have a co occurring substance use disorder."

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"There are no long-term studies that show what kind of impact this medication will have on a child's development."

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"Lithium has for many years been the treatment of choice for bipolar disorder, as it can be effective in smoothing out the mood swings common to this disorder, but its use must be carefully monitored, as the range between an effective dose and a toxic one is small."

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